Colorectal cancer CRC is the third most common neoplasm, and its prevalence increases with age and with social and economic status urbanization. Studies have shown an increased risk of cancer in DM patients, especially along the digestive tract, including CRC, without being able to find a clear pathogenic link between the two chronic diseases.
In this review we intend to analyze the relationship between DM and CRC in terms of epidemiology and risk factors. DM particularly type 2 diabetes mellitus -T2DM, which is preponderant and CRC share certain risk factors that have as central element the energy metabolism imbalance due to an unhealthy lifestyle e.
Biopsy and FNAC are invasive procedures, especially in the case of deeply located tumors, and may present severe complications such as infection, bleeding, or inflammation. More importantly, they also carry the risk of seeding tumor cells around the sampling area. Indeed, detached cells can be cleared by interstitial fluids to lymph nodes, or into the veins draining the tissue, thus entering the circulation.
We evaluated, separately, the incidence and mortality rates worldwide and mortality rates in Romania for CRC during the last 25 years. For DM we evaluated its prevalence worldwide during the last 20 years.
Colorectal cancer epidemiology incidence mortality survival and risk factors
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Colorectal Cancer Screening
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